I would put together a crack team of nerds with to much time on their hands and useless degrees that will however be useful for infiltrating a highly protected and secret research facility.
I'll need an astrophysicist, a biologist, a forensic scientist, probably an MD, an IT guy aaaaand... a physicist.
The astrophyscist and the physicist work together to build a giant laser in space, I will call it... the Doom Planet! It smashes a hole in the wall of the facility which the team climb through.
The biologist and MD are there to be support personel. The forensic scientist works on analysis of the various blood splatters to tell us what not to do in the puzzles, while we work our way to the storeroom.
Fuck yeah, steal everything.
The IT guy is there in case glados shows up.
Then we portal out. yeeeeeaaaaaah.