Biohazard makes much more sense now for the series. Resident Evil was appropriate for the first game, but once the series progressed more and more outside of 1 closed arena (Police Station/Lab in RE2, Town in RE3, Spanish county in RE4, Africa in RE5) it really should have changed. People put too much emphasis on name recognition and think that people are too stupid to realize when something they know has changed their name. Now that's its really focused more on the fact that it's a virus, and now a weapon of terrorism, Biohazard really matches the theme more.