There is a lot of contenders that I would have to put on a very short list. Firefly is the obvious. Top Gear managed to absolutely engulf me in spite of my complete lack of interest in cars. Family Guy and The Office practically define comedy. But overall, I'm gonna have to give the award to House. Because of its sheer breadth. Everyone I know of all age groups likes House. House is a truly interesting, multi-faceted character that appeals to the geek in everyone. Its got long term character development, and really excellent, wry humor that never gets old. Its got a heaping helping of everything you could want. And so, House takes the cake.