That damn ***** in the beginning of Dead Rising. The old annoying lady who screeches in your face, "Wheres my dog!? WHERES My DOG!!?".
She sees the ugly little poodle right outside the barricade that is keeping thousands of zombies out of the mall.... so she starts ripping apart the barricade.
Two survivors, both men, try to stop her from getting everyone killed, but she throws them off, somehow.
She gets through the barricade, gets eaten alive before she can even reach her ugly dog who looks undead anyway, and then the zombies pour in, filling the mall, and essentially making life hell on earth for those trapped in the mall.
From the first time I saw her, I hated her. To me, she was like the combination of every typical, spoiled rotten, ungrateful, selfish, and retarded "fellow" Americans I see every day. But after she fucks up everything by wreaking the barricade for her stupid dog, she elevates herself to a whole new level, and became my most hated character in gaming history.
If her NPC was still alive after that cut-scene, the minute it switched to game-play, I'd beat it to death with a lead pipe. Every time I played that game and got to that part, I'd beat her again. Every birthday of mine, I'd wake up early, load that part of the game, and brutally murder her until she shuts up and dies.
I HATE HER, and she's such a jerk.