Funniest Line In A Game?

[Get_A_Grip_]

The commentary from the PS2 era Pro Evolution Soccer games.
Oh, it was so bad.

 

[Still Life]

Mercenary: "I've got nothing else to say to yo...."

*Smash*

Mercenary: "Aahhhhhh"

Commander Shepard: "How 'bout 'goodbye'"

ME2 had some memorable lines.

 

[brunothepig]

[Nefarious' brain transmits a soap station]

Lance: Oh Janice, promise me you'll never leave me again for that Englebert.
Janice: Oh Lance!
[kissing]
Janice: you make me feel like a young boy again!
Lance: [pause] Say what?

Ratchet Gladiator. Love that game. Such inappropriate humour.

Anything. Anything from Portal.
And your uncle in Assassins Creed 2. "It's a-me, Mario!"

 

[Enigmatic Master]

Duke Nukem

"i came to kick ass and chew bubble gum and i'm all off off gum"

 

[lokun489]

well either raz's dance from psychonuats or "speedy thing goes in, speedy thing comes out"

 

[Buzz Killington_v1legacy]

Duke Nukem

"i came to kick ass and chew bubble gum and i'm all out of gum"

Nice, but they lifted that from 1988's They Live [http://en.wikipedia.org/wiki/They_Live].

One of my favorites is from the Sam and Max games:

"We are the Queen of Canada."
"I thought Rush was the Queen of Canada."

 

[icame]

Every fucking line from resident evil 1

 

[Hisshiss]

Ahhh deathspank...funniest game ever, I want to BE the guy who does his voice XD..every damn line is gold.

The second episode came out a few days ago, bought the damn thing in a heartbeat XD.

As a general rule of thumb, the best way to be like deathspank is to somehow link everything to the words Justice and Vanquish...and perhaps Dirty Orphans.

 

[Hosker]

Just about every line of dialogue from GLaDOS

 

[Sinisterspider]

This is all jokers fault what a tool he was i have to spend all day computing pi because he plugged in the overlord.

ME2 Has some real gold moments. :]

 

[Eduku]

This bit from KOTOR 2 was pretty funny

Atton Rand: Just so you Jedi know, the whole "cryptic routine" isn't mysterious, it's just irritating. If you really *can* see the future, you should be at the pazaak table.
Exile: But to know the future, one must know yourself.
Atton Rand: What was that, some kind of joke?
Atton Rand: That's what I'm talking about. "Jedi talk". You two should start your own little Jedi Academy.
Exile: But to teach, one must be willing to learn.
Atton Rand: All right, all right! Cut it out, I get it, I get it! The last Jedi in the galaxy, I get the comedian who runs around in his underwear.

Also, most of the things Joker says in Mass Effect.

 

[Impluse_101]

Any line from Deathspank

or the ever classic "I am the Milkman, my milk is delicious!"

For Quoting Psyconaughts.

 

[amppi1236]

Pippin' Apple: "Please, you have to save my brother, Red Delicious!"
Deathspank: "Is that his name or his stripper name?"

 

[rabidmidget]

Any line from Deathspank

or the ever classic "I am the Milkman, my milk is delicious!"

For Quoting Psyconaughts.

EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE!

My own certificate!

 

[aaron552]

In ME1, Renegade Shepard gets this:

Asari Council Member: Commander, is this some kind of game. Are you calling in a report just so you can cut us off again?
Commander Shepard: You know it.
Joker: That never gets old, does it?

 

[FURY_007]

ROCKET LAWNCHER!!! lol i love the metal slug games

 

[Jester00]

the dialogues from portal, especially at the bossfight.

 

[cheftacular]

"Is that all you've got, meatbag?" = HK47 is a champ.

 

[electricsoup_erman]

From Armed and Dangerous
Rexus: You are both French.
Guards: We surrender!
(no offence to french people)
Rexus is mind controlling those two guards when he says this.

EDIT: Also from Armed and Dangerous
Roman: Jonesy defuse the bomb.
Jonesy: Alright fella we'll have you out in no ... DUCK!
Explosion!
Roman: Expert touch Jonesy.