Funniest Line In A Game?

[York_Beckett]

"I don't have your stone, and f--- you anyway!" - Alone in the Dark (It's just the way he says it...)

Oh, and also:
http://www.youtube.com/watch?v=FI7FVHWYXIg&feature=related

 

[Chris^^]

I'll just pick something random.
"The moose, is loose!"

fukken' DEERHAUNTER!!!

I prefer 'I am the glovenor! pick me! I'm quite handy'

 

[WOPR]

Pretty much anything from MadWorld

Announcer #1 "Jack is Ramming Himself ageist Kojack!"
Announcer #2 "So wait a minute, Jack is ramming himself, ageist himself... we are watching the most violent mast*****ion ever"
Announcer #1 "...heh this is nothing..."

 

[coolman9899]

any thing duke nukem has or ever has said

 

[coolman9899]

OH also [youtube=CDIVcJleMb0

 

[cartographer54]

Assassin's Creed 2: "It's a-me, Mario!"

 

[Victor Yakovlev]

Haha, loved that.

 

[Azure Sky]

All your base are belong to us! =3

 

[Victor Yakovlev]

"id appreciate you having a poke at that.... uhhh... the system, not my mom."

Borderlands, Scooter

 

[Rickyvantof]

"I enjoy the sight of humans on their knees. *awkward silence* That is a joke."

Aaah, I just went through that part 30 minutes ago. One of the few times I actually laughed while playing a game. Joker is such an awesome character.

 

[Victor Yakovlev]

Company of heroes, when you click a wirbelwind in rainy weather
"rain..... open top tank.... fucking great engineering" in a thick German accent

Infantry unit in company of heroes "join the army they said, see the world they said."

anything that airborne say...

Also, star craft 2, clicking an idle SCV "AH! YOU SCARED ME!"

 

[Lolth17]

ME2, like all of them, but this one is pretty funny.

Garrus: They wouldn't give me a mirror. How bad is it?

Shepard: Hell Garrus, you were always ugly. Just slap some face paint on there and no one will notice.

And:

Shepard; Sorry, but I'm having trouble hearing you. I'm getting a lot of bullshit on this line. (I used that one irl the other day)

And:

Shepard: Hell yeah... put more stuff in... the thing stuff goes in.

 

[SulfuricDonut]

Here's two of my favorites:

-Gears of War 2
Carmine: If you wore a helmet, you wouldn't have to breathe in the dust!
Dom: Yeah, but then I wouldn't be able to see snipers very well, would I?

-Portal (practically any GladOS line)
GladOS: I was like 'we are going to kill you now' and you were like 'NO WAY!'

EDIT: And practically any SCV line in Starcraft II, including 'What, did you run out of marines?' and 'WELL BUTTER MY BISCUIT!'

 

[BenzSmoke]

Saints Row 2
After bumping into a cop, he pushes me and says, "Don't mess with me, I'm a cop on the edge!"

 

[acer840]

Anything that is said in the Borderlands Mission: Jail Break (The Secret Armory Of General Knox). Some people enjoy prison in that world a bit too much.

 

[Matthew Wilson]

LittleBigPlanet on the second level when you learn about respawning. Human encyclopedia Stephen Fry says 'Don't go throwing your controller at the cat or he might throw something back and it'll exacerbate things.'
Brilliantly random.

 

[Najal]

Portal:

"Any contact with the chamber floor will result in an 'unsatisfactory' mark on your official testing record, followed by death. Good luck!"

 

[comandertrey]

"we're gonna booze... *burp* millionares!"
alan wake

 

[Cazza]

"Game over man game over" - Zoey Left4Dead

Loved that elevator conversation. Nothing like comparing an alien attack to a zombie apocalypse. Very fitting.

 

[coldshadow]

"I enjoy the sight of humans on their knees. *awkward silence* That is a joke."

sneaky ninja.

I guess then I will go with what joker says right before:

"this is all that jokers fault, what a fool he was. I have to spend all day computing pi cause he plugged in the overlod"