I'm actually a big fan of romance in games, especially when the player is actually involved in it on some level.
As for ones that really didn't work for me, I'll have to go with the ME1 romances. Liara was about ready to climb on top of me after I had barely even met her.. that bugged me, and her character never really did develop at all. Ashley.. gah, don't even get me started. Fugly, xenophobic, religious and slightly manly. Why anyone would consider her a catch, I'd never understand. Haven't played as a female in ME1, but from my interactions with the female love interest it doesn't seem like lady Sheps had it any better.
As for ones that really didn't work for me, I'll have to go with the ME1 romances. Liara was about ready to climb on top of me after I had barely even met her.. that bugged me, and her character never really did develop at all. Ashley.. gah, don't even get me started. Fugly, xenophobic, religious and slightly manly. Why anyone would consider her a catch, I'd never understand. Haven't played as a female in ME1, but from my interactions with the female love interest it doesn't seem like lady Sheps had it any better.