I always found it funny how my name (Carlos) is in most games I play. Saint's Row 2 was already mentioned many times. In Fallout 3 I just had to give Carlos the Beggar outside of Rivet City a water every time I had the chance. Lastly, in the intro to Black Ops had a man named Carlos, while Sgt. Woods had cigarettes with the brand of Garcia, which is my last name. Very weird.
Since Dead Space has been mentioned too much, I will go ahead and say Diablo. The whole thing was creepy, but finding the wounded man outside the cathedral was terrifying. That cathedral was also the scariest looking building I have seen in my life.