Ehh, Fallout 3 and Red Dead made me feel nothing for the innocent bystanders and such so there really was no issue there. The only game that has ever had me at an impasse was Bioshock 1. My first play through, I sat at the choice screen on whether to save or harvest the little girl for like half an hour. Finally decided I really just couldn't kill the little girl despite my normally being an evil character and saved her. This same mentality carried on to Bioshock 2 as well. I guess I'm pretty okay with doing evil things in games as long as it isn't towards little girls?