No, because it's just part of who he is overall. So, he's different to me than a random person using the word.
So with THAT said, the casual and loose way the word ****** is slung around by so many people is EXTREMELY offensive to me, because we ALL know where the word does come from, and to say "it's not about gay people" is completely false. The word is directly connected to homosexuals, stereotypes of homosexuals, and negativity in general. Whenever I hear the word, I cringe, and quite frankly, it's one of those things that make me look at someone differently. I could never ever use the word without feeling sick.
I'm not offended in this case because it's part of Yahtzee's overall schtick, but when people say "that's so gay" and ******, it's solely because it's OK to use and essentially be anti-gay. People say words evolve and change, but is that true? You don't hear the n-word being used incessantly. You don't hear **** being used against women incessantly. You don't even here dyke being used incessantly. It's gay slurs being used incessantly, and they have become so normalized, people are numb to them and can't even comprehend why others are offended by the word. There is a reason for that. It's not "just because."