You guys are all missing the point. You don't understand. You weren't there at the beginning. Fallout is about one place. It has only ever been about one place. It is the STORY of that ONE PLACE. And that place is California and the areas around it. Every time they start to stray from California, the games suck. (The exception being Fallout 3, which gets a pass)
Fallout 2 is to this day still the greatest game ever made, if for no other reason then these three words. Lesbian Shotgun Wedding. At that point, fallout 2 won video game design for all time. Both 1 and 2 had something special going for them. A wicked sense of humor combined with very self-aware satire.
For the first time in 13 years, fallout is back in the hands of its creators. Feargus Urquhart, and Chris Avellone. Tim Cain is unfortunately doing his own thing, but Black Isle studios was, hands down, the best development team ever. And most of them are at obsidian. Now Bethesda I will give credit to for resurrecting fallout. And they were then smart enough to hand it off to its parents. Bethesda/Obsidian have a LOT of potential. More so even than squeenix. To those of you suggesting that Fallout should die with dignity... you first.
There have been 4 fallout games that matter. 1, 2, 3 and vegas. The rest never happened. Now the only piece missing is Tim Cain's warped sense of humor. But there are a lot of people with warped senses of humor.
So, tl;dr
Keep fallout in California where it freaking belongs. If you MUST switch location, do like vegas did and keep it close, and LET US GO BACK THERE. Klamath has gotten huge since fallout 1. I wanna see the new metropolis.