@CA If they get Your Fate is Thrice Sealed on the first turn I've found it can get kinda rough, especially if the get more than one land since they can end up with a two turn head start on you. Once I had just cast Ulamog and he got the one that lets him exile a creature with flying a creature without flying and a graveyard, which is probably the only out to Ulamog in the whole game. And the one that destroys all nonland permanents target player controls is pretty brutal as well. But you're right, now that I think about it there aren't many that do anything on the first turn.