Anything said by your character in DA:O, mainly because they believe that if its said once, it should be said 100,000 times!
YA RANEN!*
Every Monolith enemy in Stalker, Call of Pripyat; I try and stealth Pripyat itself just because of that. Actually, anything said by Stalkers in ceasefire zones, mainly because you here it 100 times each visit.
Mass Effect 1's Human, Turian or Asari enemy's 100,000 shouts per battle... why oh why couldn't they have either given them more to say or at least made them speak less...
"Watch out!"
"Enemies everywhere!"
"I will destroy you!"
NOOOOOOOOOOOOOOOOOOOOOOOOOO!
*Yes I know you're injured, now just shut up, drop down and die! Its especially bad when they say it AFTER they're dead.