What's the funniest video game line ever?

[SimuLord]

"Take these radiation chems as my way of saying 'sorry I twisted your DNA like a kitten with a ball of yarn.'" - Moira Brown

 

[morsy]

"You are going to tell me about the man with the blue car"

 

[Cain_Zeros]

"Head him off at the pass? Who the hell says that? What is he some kind of f**king cowboy?"-Krunk, Metal Arms: Glitch in the System

 

[Fox242]

"My mother's my sister!"
-random pedestrian, GTA III

"We may need you to play Twing Twang."
-Nariko, Heavenly Sword

"But I wrote that for you1"
-frightened minstrel, Assassin's Creed 2

 

[WestMountain]

"You will just have to FUCK it"

 

[theownerer]

"Francis, is there anything you don't hate?"
"Well, I don't hate vests."
- Bill and Francis in L4D

I thought he said "I dont hate this" as in killing zombies.

 

[Nickolai77]

"Incoming fire has right of way" and "Team work is essential, it gives the enemy somebody else to shoot at" both from Call of Duty 4

 

[AVATAR_RAGE]

"Wonderful! Time for a celebration... Cheese for everyone! Wait, scratch that. Cheese for no one. That can be just as much of a celebration, if you don't like cheese. True?"

One of Sheogorath's words of wisdom

 

[Audioave10]

"I love my Job"
spoken by a cop just before a grenade landed at his feet (GTA 4)

 

[Robert632]

"Your right hand comes off?"

Leon, Resident Evil 4. Retarded dialoge at it's finest.

 

[ntw3001]

Final Fantasy 7, where Cloud goes into his hometown and find it full of cloaked people saying something about a reunion. Eventually, he breaks down and wails 'I DON'T EVEN KNOW WHAT A REUNION IS!'

 

[hazabaza1]

Francis-"Guys, look out for that steam valve."
Zoey-"I love steam!"
Francis-"Yeah, steam's okay."

You so silleh, Valve.

 

[Burningsok]

Look at all that juuuuice! - Cole from Gears

 

[TheTrojanBadger]

Pretty much anything from the Shanghai Zoo level in Army of 2: The 40th Day. The best one had to be Salem see in the dead elephant and screaming "NOOOOO!! DUMBO!!".

Also, in Mercenaries 2, when you have to deliver the truck full of parrots.
Fiona-"What's in the boxes?"
Swedish dude(can't remember his name)-"Parrots"
Fiona-"Oh. Okay."

 

[JokerCrowe]

I can think of so many I could be here all night. Basically everything GLaDOS says in Portal:

"Any contact with the chamber floor, will result in an unsatisfactory mark on your offical testing record. Followed by death. Good luck!!"

Almost every line in, Psychonauts:
Raz: "My name..."
Coach Oleander: "Begins with a 'd'"
Raz: ...is Razputin, but you can call me, "Raz".
Just as an example.

TimeSplitters, any game really:
Jo-Beth *kicks Cortez in the crotch*
Jo-Beth:"Hey! you're no Zombie"
Cortez: *high voice* "Yeah! I'm aware of that..."

 

[TheDuckbunny]

Can't beat this.

 

[Conkzerton]

Fallout 3 makes me laugh a lot.. But strangely my favourite is: "my humour emmiter array requires charging"

Oh and some Brutal Legend stuff. "Everything in that general direction must die!" comes to mind.

 

[Grensen]

"Victor "goddamn" Sullivan" everytime that makes me giggle... Pretty much any scene Sully is in makes me happy