Mass Effect 2
Kal'Reegar - "I'm not going to die of an infection on the battlefield, that's just insulting!"
Jacob - "Saving the Citadel is like wetting yourself in black pants. It's a warm feeling but nobody notices."
Garrus - "Of course you could have done this mission without me. Not as stylishly of course, but still..."
Garrus - "How do I look?"
Shepard - "Hell Garrus, you always looked ugly."
Garrus - "Well I was always getting the girls. I suppose it's your turn to get some action."
Baldur's Gate
Minsc - "When the going gets tough, someone hold my rodent."
Dragon's Age
Shale - "Let's go squish something. That's a girly thing to do!"
Shale - "Did I kill him? I hope I did. I hope the last command he gave was 'Golem, stop crushing me'."