This.Freaky Lou said:Fallout 3. It's the intro sequence; takes so long and so little variation each time.
Leaving aside my other issues with FO3, any time I do summon up the drive to try it just-one-more-time just plodding through that interminable intro in Vault 101 drains my will to go on. What makes it worse is that up to the point you wake up on what will be your last day in the Vault nothing has the slightest consequence, and is so heavily scripted it may as well be a 20 minute cutscene.
Others - the one forced stealth level in Return to Castle Wolfenstein... and that Krogan Battlemaster you run into early on in Mass Effect has put paid to at least one attempt to replay that game.