If Optimus Prime lived in Newcastle, England, he'd be Optimus-upon-Tyne.
If Optimus Prime was capable of producing his own source code, he'd be an Optimus Quine.
If Optimus Prime was a Final Fantasy 7 Enemy Skill, he'd be Optimus Trine.
If Optimus Prime was a Cowboy Bebop character, he'd be Optimus Ein.
... Or, for a variation on the theme:
If Optimus Prime joined the police force, he'd be Coptimus Prime.
If Optimus Prime spun around really quickly on one toe, he'd be Toptimus Prime.
If Optimus Prime completely failed at the box-office, he'd be Floptimus Prime.
If Optimus Prime developed an obsession for retail therapy, he'd be Shoptimus Prime.
If Optimus Prime had a set of traffic-lights, he'd be Stoptimus Prime.
If Optimus Prime wasn't good enough to be allowed to stay with the Autobots, he'd be Droptimus Prime.
If Optimus Prime was a brony, he'd be Cloptimus Prime.
If Optimus Prime had each of his limbs tied to a particular keyboard button press and was forced to run, he'd be QWOPtimus Prime.
If Optimus Prime was a fan of experimental Jazz, he'd be Beboptimus Prime.
If Optimus Prime served as a dramatic accessory, he'd be Proptimus Prime.
If Optimus Prime was used to absorb kitchen or bathroom spillages, he'd be Moptimus Prime.
If Optimus Prime was a British Northerner, he'd be Ey-Optimus Prime.
While if he was from the midlands, he'd probably be Shroptimus Prime.