Thesis: Vampires were not ruined because of one series. Summary at the end.
Mythological refers to creatures from stories. Much like how Cryptological refers to mysteries, and biological refers to organic, cellular, proven life. Cthulhu counts, even if he's not scary. How bad can he be?
In regards to this entire thread; Stephanie Meyer and young girls do not have the power to ruin or destroy anything. Vampires have slowly changed from the mindless bloodthirsty animated corpses they began as to (often) bisexual chess players who spend large efforts seducing and drinking from one particular person. This is a gradual evolution, a large turning point of which would have been Elizabeth Bathory, a woman who took virgins from the nearby village and bathed in their blood along with her lesbian lovers. This was credited as inspiration for Camilla, one of the oldest well-known vampire stories where the creatures in question are not mindless.
Camilla was also counted as an inspiration for Bram Stoker's Dracula. And according to a version of the book I have, so was a dream in which the author dreamt the scene where the count pulls the young man away from the coven of female vampires and says "He is mine!"
Summary (aka TL;DR): Sentient vampires have bisexual tendencies, original vampires were solo zombie hordes.