I don't really know what to expect from DA2, since the news about the game have been pretty much "We changed everything, while keeping everything the same as the first game!". Not really sure whether I'll get a medieval Mass Effect, or a Baldur's Gate sequel.
I don't have much expectations for Witcher 2, I liked the first game, but I'm not really a "fan". I'll probably get it, whenever it comes, and like it.
Skyrim'll definitely be a good sandboxy game, although much like Witcher 2, I'm not a massive fan, and I won't shed tears if it fails to deliver.
I'd have to say I'm looking most forward to DA2, although I have my doubts about it. If I had to guess, Witcher 2 will probably be the best gaming experience out of the three.