Getting rid of Split-Screen and bots in the majority of multiplayer these days, games are much more fun and a social experience when the people are actually there rather than being forced to sit in your own houses to play together. And the removal of bots is very irritating due to those few games that have split screen but leave you with the choice of playing 4 player with people around you or up to 24 player on different machines, plus not having bots makes it impossible to get better at multiplayer without enduring being killed every few seconds.
Ensemble Studios shutting down, no more online support for AoM, which had some incredible online gameplay.
Spyro the Dragon after the original trilogy; Year of the Dragonfly was okay at best but not a patch on the originals and everything afterwards was not worth a mention. Same applies for Crash Bandicoot although the point that got bad is less clear.
Jade Cocoon 2, taking a dark and interesting RPG and turning it into cutesy anime. Although that thing isn't always bad in moderation (Okami), this just completely ruined the feel of what could have been a good series.
Ensemble Studios shutting down, no more online support for AoM, which had some incredible online gameplay.
Spyro the Dragon after the original trilogy; Year of the Dragonfly was okay at best but not a patch on the originals and everything afterwards was not worth a mention. Same applies for Crash Bandicoot although the point that got bad is less clear.
Jade Cocoon 2, taking a dark and interesting RPG and turning it into cutesy anime. Although that thing isn't always bad in moderation (Okami), this just completely ruined the feel of what could have been a good series.