Tomb Raider needs to go, there are only a certain amount of archaeological gold-mines in the world and Lara found the last of them around TR:3, after that they just started making shit up in unacceptable ways (in TR 1-3 they made shit up in acceptable ways).
GTA could use a break (definitely not a finish, since they're still fun, but mebbe a 5 year break so people can forget about having played 6 of the same game already and fully enjoy the new one).
Series that need a revival:
Kessen, I don't care what anyone says, it was awesome, and it could help Koei up their stock value since interest in the Dynasty/Samurai/Orochi Warriors series' has plummeted, the Gundam crossover was not a good choice.
Zone of the Enders, possibly the most fun mech games of the PS2. 'nuff said.
Destruction Derby. It was just mindless, violent fun.