While it's easy to jump the gun and condemn this bloke for "feeling her up", i think people need to stop and realise that we don't have all the facts. "Totally takes advantage of her" is a pretty heavy accusation to make. For all we know, they might grope each other from time to time - after all, we know they're close as they are best friends. Maybe she likes him as much as he likes her. Maybe he's "felt her up" before when they were both conscious and she was okay with it. Groping could be anything from simply touching her boobs, to stroking her hips, caressing her cheek, or actually putting his hand inside her pants. I think there's a pretty big gulf between touching someone's genitalia and drunkenly touching someone's breast. I'm not giving this guy a free pass; taking advantage of anyone when they're inebriated is wrong, but i wouldn't wag fingers and call him a future serial rapist without understanding all the facts first.
I would say though that this guy probably needs to explain to this girl that he likes her and it's putting stress on their friendship. It might already be obvious to her and she previously rejected his advances; again, we just don't have the facts to make any assumptions. But at the very least, he should talk over his feelings or desire for her. It might help to batten down his frustrations somewhat and stop things like this from happening again in the future.